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The existing enzymes can go through certain structural alterations and hence, the resulted function and catalytic activity allow new catalyzed pathways of reactions. In addition, modification could also enhance biochemical properties, pharmacokinetics, and stability. Enzymes can be physically modified in immobilization and encapsulation. Researchers also extent naturally occurring chemical reactions of enzymes to other chemicals such as polymers, aldehydes, imidoesters and anhydrides, to give enzymes more diverse properties. In addition, chemists have developed a large set of reactions that label the enzymes through post-expression modifications. Many properties of an enzyme may be modified to achieve that.

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